Based on the real life human defense system. Defend against evil bacteria and viruses. It's possible to build a maze like DesktopTD. The game and towers are pretty complex but once you've figure it...

A humorous tower defense game with the weirdest creeps. Build a maze of towers like the classic Desktop Tower Defense. Instructions: Select a tower from the left bottom, the click anywhere in th...

A beautiful fantasy tower defense game with a deep story behind it. Make your way up as a wizard, place the right towers to protect your land against the invading creeps.

Buy troops and tanks to place around the smuggling route. You have to stop the notorius drug trafficer that goes by the alias of Asian White Pearl. Use the mouse to buy, place and upgrade your army...

A really large TD game. Its possible to zoom in and out on the game. Defend your base in the desert. Enemies can come from the path but also other sides. Protect and upgrade. Has a useful map to se...

3 Dimensional tower defense with a very nice look. Build your towers in different short levels. A lot of RPG elements, learn more by reading the protectopedia inside the game.

Play 21 new missions for The Space Game: The hit game from The Casual Collective. Defend, repair, mine, survive and kick some ass! 4 Levels of difficulty to select from. Follow the 2 quick tutorial...

Pretty much a desktop tower defense ripoff. But it's more than just that ripoff. Very nice and useful towers in a very nice looking game. Enjoy building and upgrading your pencils, paper clips, cal...

Defending against toys like paper planes, teddy bears, toy soldiers and more. Looks simple but can be pretty challenging.

A science-fiction defense game from Packed. Build large turrets to shoot down the enemies in this beautiful game.

Tower Defence with a computer-theme. Defend yourself against spam, virusses, spyware and more. Original tower idea's to defend your computer against everything, includes upgrades ofcourse. Also som...

Second part of the Protector series. Again the 3D isometric perspective to the game and and fantasy world as theme, go through the map for a lot of missions.

A remake of Roman Sanine TD, this one looks a lot better with different enemies and towers. Build and upgrade or as they call it: Using coins, summon the heroes to kill the monsters.

Defend your planet against the incoming ships. Very nice idea for a towerdefencegame. Good luck and try to experiment with those different game modes!

Tower defense game with some additional micro management and old school pixel art art. Progress on the mini map and try to beat all 25 different maps. Use your mouse cursor to place, upgrade or sel...